Factors predicting in-hospital mortality in patients with cirrhosis hospitalized with gastro-esophageal variceal hemorrhage.
Artículo
en Inglés
| IMSEAR
| ID: sea-63695
ABSTRACT
AIM:
To identify factors at the time of admission that predict in-hospital mortality in patients with gastro-esophageal variceal hemorrhage.METHODS:
Case records of patients admitted with gastro-esophageal variceal hemorrhage between January 1998 and October 2003 were retrospectively analyzed. Relevant clinical and laboratory parameters and their relationship to mortality, were studied. Clinical parameters assessed included Child-Pugh class, ascites, portosystemic encephalopathy (PSE) and occurrence of rebleed within 24 hours of esophago-gastroduodenoscopy. The laboratory parameters assessed were hemoglobin, prothrombin time, serum bilirubin, creatinine and albumin.RESULTS:
Of the 343 patients admitted during the study period, 30 (8.7%) died in hospital. Serum bilirubin (2.4 versus 1.6 mg/dL) and serum creatinine (2.1 vs 1.1 mg/dL) levels were higher among non-survivors than among survivors. Non-survivors were also more likely to suffer from PSE (53%) than survivors (17%), while re-bleeding within 24 hours of endoscopy occurred in 40% and 5% of these groups, respectively. On multivariate analysis, serum creatinine > 1.5 mg/dL at the time of admission (p < 0.001), serum bilirubin > 3 mg/dL (p < 0.001), presence of PSE (p = 0.003) and rebleed within 24 hours of endoscopy (p < 0.001) were significant predictors of mortality.CONCLUSION:
Serum creatinine and bilirubin levels, presence of PSE and re-bleeding within 24 hours of initial endoscopy are independent predictors of mortality in patients with gastro-esophageal variceal bleeding.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pruebas de Coagulación Sanguínea
/
Femenino
/
Humanos
/
Masculino
/
Várices Esofágicas y Gástricas
/
Factores de Riesgo
/
Mortalidad Hospitalaria
/
Hemorragia Gastrointestinal
/
Cirrosis Hepática
/
Pruebas de Función Hepática
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Año:
2006
Tipo del documento:
Artículo
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