Primary biliary cirrhosis: an Indian experience.
Artículo
en Inglés
| IMSEAR
| ID: sea-64309
ABSTRACT
Primary biliary cirrhosis (PBC) is believed to be rare in India. We analyzed our data pertaining to patients with PBC seen in a tertiary referral center over a 5-year period. The diagnosis of PBC was based on liver biochemistry, histology and antimitochondrial antibodies, in the absence of biliary obstruction. Five patients, all women, were diagnosed to have PBC. Pruritus, jaundice and fatigue were the most common initial symptoms. Hepatomegaly was seen in 4 of 5 patients. Associated autoimmune diseases were present in 2 patients. All patients presented with mild hyperbilirubinemia (< or = 6 mg/dL) with disproportionately raised serum alkaline phosphatase level. AMA was positive in 4 patients. Liver biopsy showed stage III-IV disease in 3 of 4 patients. The clinical presentation and course of PBC in India are similar to the experience in the West.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Rifampin
/
Biopsia con Aguja
/
Índice de Severidad de la Enfermedad
/
Femenino
/
Humanos
/
Resina de Colestiramina
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Adulto
/
Quimioterapia Combinada
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
País/Región como asunto:
Asia
Idioma:
Inglés
Año:
2001
Tipo del documento:
Artículo
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