Evaluation of plasma serotonin concentration in acute appendicitis.
Artículo
en Inglés
| IMSEAR
| ID: sea-64643
ABSTRACT
BACKGROUND:
Due to lack of reliable biochemical/radiological markers, the diagnosis of acute appendicitis is based only on clinical features.METHODS:
We estimated plasma serotonin levels in 48 patients with acute appendicitis (histologically proven), 27 patients with abdominal pain of other etiologies, and 20 healthy controls.RESULTS:
The plasma serotonin levels were (mean +/- SD) 36.6 +/- 12.5 nmol/L, 12.5 +/- 3.6 nmol/L and 10.4 +/- 3.5 nmol/L in the three groups, respectively. The levels in patients with acute appendicitis were significantly higher (p < 0.001) than in the other groups, giving 93.8% sensitivity and 95.7% specificity to the test.CONCLUSION:
Plasma serotonin level is a reliable marker of acute appendicitis, especially in the first 48 hours.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Apendicitis
/
Humanos
/
Biomarcadores
/
Serotonina
/
Dolor Abdominal
/
Enfermedad Aguda
/
Valor Predictivo de las Pruebas
/
Sensibilidad y Especificidad
/
Diagnóstico Diferencial
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio diagnóstico
/
Estudio pronóstico
Idioma:
Inglés
Año:
1997
Tipo del documento:
Artículo
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