Increased free radical activity in burns.

ABSTRACT

In burn trauma there is excessive activity of FR at the site of injury that result in oxidative stressful state. This is reflected as elevated blood levels of LPP, UA and CLP. The fall of AA in serum appears to counteract the oxidative stress. Increased eCAT activity occurs as a metabolic response to compensate the oxidative stress. These alterations in the biochemical parameters occur parallel to the degree of burn injury. It is suggested that therapeutic use of antioxidants may be beneficial in the clinical management of burn patients.