Imipenem resistance in nonfermenters causing nosocomial urinary tract infections.
Indian J Med Sci
;
2003 Jul; 57(7): 294-9
Artículo
en Inglés
| IMSEAR
| ID: sea-67434
ABSTRACT
Nonfermenting gram-negative bacilli (nonfermenters) have emerged as important nosocomial pathogens causing opportunistic infections in immunocompromised hosts. These organisms show high level of resistance to b-lactam agents, fluoroquinolones and aminoglycosides. Imipenem is a carbapenem antibiotic, which can be very useful for treatment of infections caused by nonfermenters. Eighty-five nonfermenters causing nosocomial UTI were tested for MIC to imipenem by agar dilution method. Resistance to other antimicrobial agents was compared between imipenem sensitive (S) and resistance (R) groups. Overall 36.4% of nonfermenters were resistant to imipenem. Forty two percent of P. aeruginosa and 18.5% of Acinetobacter baumanii were imipenem resistant. Other nonfermenters showed variable resistance, resistance in Alcaligenes spp. being very high. More than 70% of the nonfermenters were resistant to ceftazidime, gentamicin and ciprofloxacin. Piperacillin and amikacin had the best in vitro susceptibility. No significant difference was found in the antibiotic susceptibility profile among imipenem sensitive (S) or resistant (R) strains.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Infecciones Urinarias
/
Humanos
/
Pruebas de Sensibilidad Microbiana
/
Imipenem
/
Infección Hospitalaria
/
Farmacorresistencia Bacteriana
/
Bacterias Aerobias Gramnegativas
/
Antibacterianos
Idioma:
Inglés
Revista:
Indian J Med Sci
Año:
2003
Tipo del documento:
Artículo
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