Electroretinographic assessment and diagnostic reappraisal of children with visual dysfunction: a prospective study.
Indian J Ophthalmol
;
2007 Mar-Apr; 55(2): 113-6
Artículo
en Inglés
| IMSEAR
| ID: sea-69811
ABSTRACT
PURPOSE:
To assess the presence or absence of a retinal cause of visual impairment using electroretinography (ERG) in children with no obvious discernable cause on ocular examination.DESIGN:
Prospective observational case series. MATERIALS ANDMETHODS:
A prospective study was carried out involving 120 children with the mean age 4.4+/-3.2 years with visual dysfunction. All children underwent ERG under general anesthesia using a special handheld mini-Ganzfeld (Kurbisfeld) dome.RESULTS:
Fifty-two (43.3%) children were male and 68 (56.7%) were female. The clinical diagnosis was as follows Leber's congenital amaurosis (LCA) (n=47), achromatopsia (n=25), congenital stationary night blindness (CSNB) (n=9) and others (unclassifiable, n=39). The visual acuity ranged from perception of light (PL) to PL with projection in children with LCA. In the rest (n=73), some sort of visually guided behavior was discernable. Following ERG, a diagnostic reappraisal resulted as follows LCA (n=49), achromatopsia (n=28), CSNB (n=4), cone-rod dystrophy (n=22), rod-cone degeneration (n=7), normal (n=8) and others (unclassifiable, n=2). Except for the two unclassifiable cases, ERG was successful in the diagnosis or exclusion of retinal dysfunction in the rest. By Pearson Chi-square test, there was a statistically significant association between the clinical and ERG diagnosis (P < 0.001).CONCLUSION:
LCA was the commonest cause of visual dysfunction in our series. A statistically significant correlation between clinical and electrophysiological diagnosis was seen. ERG helped in firmly establishing the presence or absence of global retinal dysfunction in the majority (118/120) of pediatric patients with visual dysfunction.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pronóstico
/
Retina
/
Femenino
/
Humanos
/
Masculino
/
Agudeza Visual
/
Preescolar
/
Defectos de la Visión Cromática
/
Ceguera Nocturna
/
Baja Visión
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
2007
Tipo del documento:
Artículo
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