Anti-insulin antibodies and retinopathy in juvenile onset type-1 diabetes.
Indian J Ophthalmol
;
1991 Oct-Dec; 39(4): 174-5
Artículo
en Inglés
| IMSEAR
| ID: sea-70273
ABSTRACT
Juvenile diabetics have severe loss of beta cell function and require replacement therapy with insulin. Insulin antigenicity can produce anti-insulin antibodies resulting in allergic reactions and insulin resistance. The role of insulin-anti-insulin antibody complexes in the development and progress of chronic diabetic complications like microangiopathy is not very clear. In the present study, there was statistically a significant trend of higher insulin antibody binding levels in IDDM patients who developed retinopathy. Though there was a trend of higher insulin antibody in IDDM patients with retinopathy, there was no association between insulin antibody and HLA antigen which some authors have reported.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Prueba de Histocompatibilidad
/
Radioinmunoensayo
/
Antígenos HLA-B
/
Diabetes Mellitus Tipo 1
/
Retinopatía Diabética
/
Anticuerpos Insulínicos
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
1991
Tipo del documento:
Artículo
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