Effect of combination antiretroviral therapy on cytomegalovirus retinitis.
Indian J Ophthalmol
;
2002 Mar; 50(1): 29-33
Artículo
en Inglés
| IMSEAR
| ID: sea-71213
ABSTRACT
PURPOSE:
To study the various changes in the course of cytomegalovirus (CMV) retinitis following combination antiretroviral treatment.METHODS:
Combination antiretroviral treatment was given to 12 patients with active CMV retinitis following which all anti-CMV medications were discontinued once the CD4 cell counts were > 100/mm3 for 3 months.RESULTS:
The median CD4 cell count increased from 36.5/mm3 (range, 3-74/mm3) at baseline to 175.5/mm3 (range, 97-410/mm3) at 3 months. No patient had reactivation of CMV retinitis or developed extraocular CMV infection during median follow-up of 16.7 months. In one patient with peripheral active CMV retinitis, the retinitis resolved completely and remained so throughout the follow-up period without specific anti-CMV treatment. Five (41.7%) patients had immune recovery vitritis.CONCLUSION:
Patients receiving combination antiretroviral treatment following treatment for CMV retinitis have better control of CMV retinitis but immune recovery vitritis is a common sequelae. Reactivation of CMV retinitis is common in patients who discontinue combination antiretroviral treatment.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Antivirales
/
Femenino
/
Humanos
/
Masculino
/
Linfocitos T CD4-Positivos
/
Agudeza Visual
/
Estudios Prospectivos
/
Estudios de Seguimiento
/
Resultado del Tratamiento
/
Infecciones Oportunistas Relacionadas con el SIDA
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
2002
Tipo del documento:
Artículo
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