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Role of prophylactic intravitreal antibiotics in open globe injuries.
Indian J Ophthalmol ; 2003 Mar; 51(1): 39-44
Artículo en Inglés | IMSEAR | ID: sea-71221
ABSTRACT

PURPOSE:

To determine the efficacy of prophylactic intravitreal antibiotics in reducing the incidence of endophthalmitis after trauma.

METHODS:

This was a prospective, randomised, case control study of 70 consecutive patients with open globe injury. The patients were prospectively randomised into group I (32 eyes) and group II (38 eyes). Group I patients were given prophylactic intravitreal injection of vancomycin 1 mg and ceftazidime 2.25 mg at the conclusion of primary repair. Group II patients were not given prophylactic intravitreal antibiotics. All the patients received intravenous ciprofloxacin.

RESULTS:

The incidence of endophthalmitis was higher in group II (7 of 38 eyes; 18.42%) compared to group I (2 of 32 eyes; 6.25%). Both the patients who developed endophthalmitis despite prophylactic intravitreal antibiotics in group I had an initially undetected intraocular foreign body (eyelash) in the vitreous cavity.

CONCLUSIONS:

Prophylactic intravitreal broad spectrum antibiotic injection decreases the risk of post-traumatic endophthalmitis.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Vitrectomía / Cuerpo Vítreo / Femenino / Humanos / Masculino / Vancomicina / Lesiones Oculares Penetrantes / Ceftazidima / Niño / Preescolar Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional / Factores de riesgo Idioma: Inglés Revista: Indian J Ophthalmol Año: 2003 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Vitrectomía / Cuerpo Vítreo / Femenino / Humanos / Masculino / Vancomicina / Lesiones Oculares Penetrantes / Ceftazidima / Niño / Preescolar Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional / Factores de riesgo Idioma: Inglés Revista: Indian J Ophthalmol Año: 2003 Tipo del documento: Artículo