Role of prophylactic intravitreal antibiotics in open globe injuries.
Indian J Ophthalmol
;
2003 Mar; 51(1): 39-44
Artículo
en Inglés
| IMSEAR
| ID: sea-71221
ABSTRACT
PURPOSE:
To determine the efficacy of prophylactic intravitreal antibiotics in reducing the incidence of endophthalmitis after trauma.METHODS:
This was a prospective, randomised, case control study of 70 consecutive patients with open globe injury. The patients were prospectively randomised into group I (32 eyes) and group II (38 eyes). Group I patients were given prophylactic intravitreal injection of vancomycin 1 mg and ceftazidime 2.25 mg at the conclusion of primary repair. Group II patients were not given prophylactic intravitreal antibiotics. All the patients received intravenous ciprofloxacin.RESULTS:
The incidence of endophthalmitis was higher in group II (7 of 38 eyes; 18.42%) compared to group I (2 of 32 eyes; 6.25%). Both the patients who developed endophthalmitis despite prophylactic intravitreal antibiotics in group I had an initially undetected intraocular foreign body (eyelash) in the vitreous cavity.CONCLUSIONS:
Prophylactic intravitreal broad spectrum antibiotic injection decreases the risk of post-traumatic endophthalmitis.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Vitrectomía
/
Cuerpo Vítreo
/
Femenino
/
Humanos
/
Masculino
/
Vancomicina
/
Lesiones Oculares Penetrantes
/
Ceftazidima
/
Niño
/
Preescolar
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio observacional
/
Factores de riesgo
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
2003
Tipo del documento:
Artículo
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