Immunoassay of serum muramidase (lysozyme) in ocular diseases.
Indian J Ophthalmol
;
1987 ; 35(5-6): 103-7
Artículo
en Inglés
| IMSEAR
| ID: sea-71353
ABSTRACT
Serum levels of muramidase activity were measured in 162 patients with different ocular diseases and 84 healthy subjects by electro-immuno-diffusion technique. We demonstrated for the first time that electro-immuno-diffusion technique could be successfully applied for the estimation of serum muramidase concentrations. Serum muramidase was found to be high in significant number of cases with granulomatous uveitis, tuberculous keratitis, central serous retinopathy and Eales' disease. Tuberculosis was presumed to be the cause in them by the process of exlusion. Patients with high serum muramidase activity were subjected to anti-tubercular treatment with a marked clinical improvement. It is suggested that high serum muramidase could be an useful parameter in deciding the line of treatment in patients with ocular diseases of uncertain etiology. Serum muramidase concentrations showed return to normal levels with the clinical improvement of the diseases with treatment. It increased again with the re-appearance of the activity of the diseases.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Inmunoensayo
/
Muramidasa
/
Oftalmopatías
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
1987
Tipo del documento:
Artículo
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