Serological responses to hepatitis B virus infection in multi-transfused thalassemic children.
Indian Pediatr
;
1992 Jan; 29(1): 73-7
Artículo
en Inglés
| IMSEAR
| ID: sea-7150
ABSTRACT
One hundred children with beta-thalassemia major were studied prospectively. A one time analysis of serum samples was carried out for a battery of hepatitis B viral markers viz., HBsAg, anti-HBs and anti-HBc. Seven mutually different serological patterns were observed. The commonest profile seen in 49 patients was a combined seropositivity for anti-HBc and anti-HBs indicating past HBV infection with persisting immunity. Definite evidence of active HBV infection (seropositivity for HBsAg and/or HBeAg) was demonstrated in 10 cases, six of these were HBsAg positive. Anti-HBc positivity alone was detected in 17 patients. The remaining 24 children were seropositive for anti-HBs alone suggesting a possible passive transmission of anti-HBs through blood transfusion.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Talasemia
/
Transfusión Sanguínea
/
Humanos
/
Niño
/
Preescolar
/
Países en Desarrollo
/
Hepatitis B
/
Anticuerpos contra la Hepatitis B
/
Antígenos de Superficie de la Hepatitis B
/
India
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
1992
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS