Clinico-biochemical study of experimental complicated cataracts.
Indian J Ophthalmol
;
1991 Oct-Dec; 39(4): 148-50
Artículo
en Inglés
| IMSEAR
| ID: sea-71885
ABSTRACT
Clinically observed complicated cataracts, generally do not have a definite causal factor. We studied the effects of E. coli toxin injected suprachoroidally, to simulate the effect of toxins released by extraocular organisms on the lens. 79.2% of eyes had a definable cataract at the end of the 6th week of observation. The biochemical changes portrayed an increased oxidative activity in the lens, evidenced by a fall in glutathione concentration, and the consequent tertiary reorientation of proteins to increase insoluble proteins, forming a cataract.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ácido Ascórbico
/
Conejos
/
Catarata
/
Lipopolisacáridos
/
Cristalinas
/
Modelos Animales de Enfermedad
/
Endotoxinas
/
Escherichia coli
/
Cristalino
/
Animales
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
1991
Tipo del documento:
Artículo
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