Utility of silver-colloidal staining method in the diagnosis of medulloblastoma.
Indian J Pathol Microbiol
;
1994 Jan; 37(1): 39-43
Artículo
en Inglés
| IMSEAR
| ID: sea-72680
ABSTRACT
Histopathological features of medulloblastomas are usually distinctive. However in rare instances, a distinction between the neoplastic cells of medulloblastoma and the neurones in the cerebellar internal granular layer becomes difficult at light microscopic level. In order to distinguish presence of argyrophilic Nucleolar Organizer Regions (Ag-NORs) was analysed in the paraffin sections of medulloblastoma as well as in the cerebellar internal granular layer. The neoplastic cells in medulloblastoma contained a mean 4.78 Ag-NOR per nucleus while the neurones in cerebellar internal granular layer contained a mean Ag-NOR 0.90 +/- 0.12 per nucleus. Compound Ag-NORs were present in the cells of medulloblastoma while they were absent in the neurones of cerebellar internal granular layer. The results of this study indicate that Ag-NOR technique may be useful in an uncommon situation, where a histopathological distinction between cells of medulloblastoma and neurones in the cerebellar internal granular layer becomes difficult.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Células de Purkinje
/
Humanos
/
Corteza Cerebelosa
/
Neoplasias Cerebelosas
/
Tinción con Nitrato de Plata
/
Meduloblastoma
/
Región Organizadora del Nucléolo
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
1994
Tipo del documento:
Artículo
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