Immune status of children suffering from minimal change nephrotic syndrome.
Indian J Pathol Microbiol
;
1992 Jul; 35(3): 171-9
Artículo
en Inglés
| IMSEAR
| ID: sea-73310
ABSTRACT
Twenty five children suffering from minimal change nephrotic syndrome were studied for immunological alterations at different stages of this disease i.e., onset, relapse and remission. Changes were found mainly at onset and during relapse in the form of altered helper and suppressor cell ratio, depressed delayed cutaneous hypersensitivity reaction, decreased S-IgG bearing lymphocytes with low serum IgG concentration, and increased S-IgM bearing lymphocytes with high serum IgM concentration. Majority of these parameters returned to normal values during remission. Serum IgE was found high at all stages of this. These alterations suggest defects in cell mediated immunity resulting in secretion of some substance which modifies the glomerular anionic charges.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Recurrencia
/
Femenino
/
Humanos
/
Masculino
/
Niño
/
Preescolar
/
Corticoesteroides
/
Inmunidad Celular
/
Lactante
/
Formación de Anticuerpos
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
1992
Tipo del documento:
Artículo
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