Cell adherence--a determinant of virulence in Yersinia enterocolitica.
Indian J Pathol Microbiol
;
2006 Jan; 49(1): 49-50
Artículo
en Inglés
| IMSEAR
| ID: sea-73641
ABSTRACT
The adherence of pathogenic bacteria to eukaryotic cells plays a central role in their ability to colonize the mucosal epithelial surfaces. The adherence by Y. enterocolitica to the mucosal surface of the gut is the initiating event leading to penetration of mucosa. Adhesion of 10 probable pathogenic and one non-pathogenic isolate was studied using ileum and colon epithelial cells of mouse for 90 minutes. Adhesion study revealed that isolates of Y. enterocolitica had a good adhesive property while non pathogenic showed negligible adherence. All isolates showed better adherence to colon epithelial cells. The organism continued to be excreted in faeces up to 8-10 days after oral feeding. Adhesion positive isolates were found to be virulent when tested in mice for diarrhoea and death. Adhesion was found to be thermoregulated.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Virulencia
/
Yersinia enterocolitica
/
Yersiniosis
/
Adhesión Bacteriana
/
Análisis de Supervivencia
/
Células Cultivadas
/
Colon
/
Diarrea
/
Células Epiteliales
/
Heces
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2006
Tipo del documento:
Artículo
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