Immunochemical studies in Wilson's disease.
Indian J Pathol Microbiol
;
2001 Jul; 44(3): 301-4
Artículo
en Inglés
| IMSEAR
| ID: sea-74145
ABSTRACT
The present study deals with a total of 28 cases of Wilson's disease, 50 normal individuals alongwith siblings and parents of eight cases. Male predominance (18 out of 28 cases), a median age of 11 years and universal presence of Kayser-Fleischer (K. F.) ring marked the cardinal features. Furthermore, 11 patients had hepatic-neural presentation while two had only the K. F. Ring without clinical abnormality. Single Radial Immunodiffusion (SRID) as the absolute quantitative procedure revealed a profound deficiency of ceruloplasmin with the levels ranging anywhere between 0.5 mg/dI to 23 mg/dI amongst the patients of Wilson's disease. The data from siblings and parents also revealed deficiency in 15 out of 23 serum samples when subjected to disc electrophoresis-benzidine screening procedure.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Electroforesis de las Proteínas Sanguíneas
/
Femenino
/
Humanos
/
Masculino
/
Ceruloplasmina
/
Estudios de Casos y Controles
/
Niño
/
Preescolar
/
Adolescente
/
Inmunodifusión
Tipo de estudio:
Estudio observacional
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2001
Tipo del documento:
Artículo
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