DNA aneuploidy in invasive carcinoma of the uterine cervix.
Indian J Pathol Microbiol
;
2000 Jul; 43(3): 265-9
Artículo
en Inglés
| IMSEAR
| ID: sea-75250
ABSTRACT
Forty cases of squamous cell carcinoma and twenty cases of adenocarcinoma of the cervix were subjected to DNA ploidy analysis to find out the frequency of aneuploid DNA pattern in different types of invasive carcinoma of the uterine cervix and their possible correlation with the clinical stage and age of the patients. From the DNA analysis an increasing trend of DNA aneuploidy was observed from well differentiated (63.6%) to moderately differentiated (70.8%) to poorly differentiated squamous cell carcinoma (83.3%). However, 85% adenocarcinomas of endocervix showed aneuploid DNA pattern. It indicates that aneuploidy increases with tumour dedifferentiation and further confirms the importance of DNA ploidy as a high risk indicator.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Anciano
/
Femenino
/
Humanos
/
ADN de Neoplasias
/
Carcinoma de Células Escamosas
/
Adenocarcinoma
/
Neoplasias del Cuello Uterino
/
Cuello del Útero
/
Adulto
/
Aneuploidia
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2000
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS