Induction of resistance to fluoroquinolones in clinical and environmental isolates of Pseudomonas aeruginosa.
Indian J Pathol Microbiol
;
2007 Jan; 50(1): 94-6
Artículo
en Inglés
| IMSEAR
| ID: sea-75504
ABSTRACT
An attempt to induce resistance to ciprofloxacin in vitro was made against clinical and environmental isolates of Pseudomonas aeruginosa. This in vitro manipulation of strains resulted in the increase of minimum inhibitory concentration from 0.4 microg/ml to 1 microg/ml of the original strains to 9.0 to 12.5 microg/ml indicating development of resistance to ciprofloxacin and a major decrease in the size of zone diameters of norfloxacin and ofloxacin indicating cross resistance to these agents. Results indicate the induced resistance to ciprofloxacin can promote development of cross resistance to other fluoroquinolones. This suggests that caution should be taken while using fluoroquinolones for the treatment of Pseudomonas aeruginosa infections.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pseudomonas aeruginosa
/
Infecciones por Pseudomonas
/
Humanos
/
Pruebas de Sensibilidad Microbiana
/
Fluoroquinolonas
/
Farmacorresistencia Bacteriana
/
Farmacorresistencia Bacteriana Múltiple
/
Microbiología Ambiental
/
Antibacterianos
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2007
Tipo del documento:
Artículo
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