Impact of availability of oral hydrocortisone on growth of children with CAH.
Indian J Pediatr
;
2005 Apr; 72(4): 301-3
Artículo
en Inglés
| IMSEAR
| ID: sea-78411
ABSTRACT
OBJECTIVES:
1. To compare growth parameters of patients with Congenital Adrenal Hyperplasia (CAH) managed on Prednisolone (PR) before and on Hydrocortisone (HC) after its availability in India. 2. To compare growth parameters of patients with CAH who have been on treatment with HC since diagnosis with patients managed on PR.METHODS:
Growth parameters of twelve children (8 m, 4 f) with congenital adrenal hyperplasia were retrospectively studied while on treatment with prednisolone (PR) earlier and then hydrocortisone (HC) after it became freely available in India.RESULTS:
Patients treated with PR had height Z score of -0.42, weight Z score of - 0.45, and height velocity Z score of -2.06. On HC these scores were -0.27, +0.16 and + 2.27. Patients treated with HC from the begining had a height Z Score of + 0.08, weight Z score of +0.22, and height velocity Z score of +0.68.CONCLUSION:
Hydrocortisone has a less growth effect than prednisolone and patients treated with HC from the beginning showed near normal growth.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
/
Fludrocortisona
/
Hidrocortisona
/
Prednisolona
/
Niño
/
Preescolar
/
Administración Oral
Tipo de estudio:
Estudio observacional
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Pediatr
Año:
2005
Tipo del documento:
Artículo
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