Hemophagocytic lymphohistiocytosis (HLH) presenting on the 3rd day of life.
Indian J Pediatr
;
2001 Oct; 68(10): 995-7
Artículo
en Inglés
| IMSEAR
| ID: sea-79083
ABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) embraces the frequently indistinguishable conditions, namely familial hemophagocytic lymphohistiocytosis (FHLH), sporadic hemophagocytic lymphohistiocytosis (SHLH) and virus associated hemophagocytic syndrome (VAHS). The disease is very rare and invariably lethal. Evidence suggests that the disease may be due to an inherited defect in immunoregulation that predisposes to an uncontrolled proliferation of activated histiocytes in response to a stimulus such as viral infection. We report here a 3-day-old neonate with confirmed HLH who had a stormy course and a fatal outcome to the disease process, in spite of early chemotherapy. To our knowledge, we believe this is the youngest reported case of HLH from Middle East. No familial or infective cause could be attributed.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Masculino
/
Recién Nacido
/
Histiocitosis de Células no Langerhans
/
Resultado Fatal
Idioma:
Inglés
Revista:
Indian J Pediatr
Año:
2001
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS