Neonatal screening for glucose-6-phosphate dehydrogenase deficiency.
Indian J Pediatr
;
2005 Oct; 72(10): 835-7
Artículo
en Inglés
| IMSEAR
| ID: sea-79336
ABSTRACT
OBJECTIVE:
This study was carried out to detect the incidence of erythrocytic Glucose-6 -Phosphate dehydrogenase (G-6-PD) deficiency, to compare the incidence of hyperbilirubinemia in G-6-PD deficient neonates as compared to G-6-PD normal neonates and to asses the usefulness of neonatal screening for G-6-PD deficiency.METHOD:
In a retrospective hospital based study 2,479 male and female neonates consecutively born at Indraprastha Apollo hospital between July 1998 to June 2003 who were screened for G-6-PD levels were evaluated for the incidence of G-6-PD deficiency.RESULTS:
Incidence of G-6-PD deficiency was found to be 2.0%. Incidence in males was 283% and female was 1.05%. The incidence of hyperbilirubinemia was found to be 32% in G-6-PD deficient neonates which was significantly higher than the incidence of hyperbilirubinemia in neonates with normal G-6-PD, which was 12.3% (P< 0.001).CONCLUSION:
Our data suggests that neonatal screening for G-6-PD deficiency is a useful test for preventing and early treatment of complications associated with it.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fototerapia
/
Bilirrubina
/
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
/
Factores Sexuales
/
Estudios Retrospectivos
/
Estudios de Cohortes
/
Factores de Edad
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Factores de riesgo
/
Estudio de tamizaje
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Pediatr
Año:
2005
Tipo del documento:
Artículo
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