Oxidative stress, phototherapy and the neonate.
Indian J Pediatr
;
2000 Nov; 67(11): 805-8
Artículo
en Inglés
| IMSEAR
| ID: sea-80929
ABSTRACT
Phototherapy is the most widely used form of therapy for unconjugated hyperbilirubinaemia. Its non-invasive nature and few side effects reported earlier have led to the assumption that it is innocuous. Recent research has revealed that phototherapy is a photodynamic stress and can induce lipid peroxidation. There is increasing evidence that many severe diseases of the neonate are caused by oxidative injury and lipid peroxidation. In the present communique, we review the oxidative susceptibility of the neonate and the evidence now available that phototherapy induces oxidative stress. Although intensive phototherapy (up to 40 mwatt/cm2/nm) has been reported to be increasingly effective, a little caution, we believe is warranted, till more definite data in the human neonate, help resolve the issue.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fototerapia
/
Bilirrubina
/
Humanos
/
Recién Nacido
/
Peroxidación de Lípido
/
Estrés Oxidativo
/
Ictericia Neonatal
Idioma:
Inglés
Revista:
Indian J Pediatr
Año:
2000
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS