Paracetamol poisoning in children.
Indian J Pediatr
;
1998 May-Jun; 65(3): 393-400
Artículo
en Inglés
| IMSEAR
| ID: sea-83797
ABSTRACT
Paracetamol (acetaminophen) has become an antipyretic drug of choice. Due to its widespread use, toxicity secondary to overdose has increased in recent years. Children are especially vulnerable to accidental exposure due to non availability of child proof containers in India. The main clinical features of acute toxicity include anorexia, vomiting, abdominal pain, jaundice, hematuria and metabolic acidoses. Diagnosis is based on history and laboratory findings of acidosis and abnormal liver function tests. N-acetylcysteine is the specific antidote. This article reviews in detail the toxicokinetics, pathophysiology, clinical features and management of paracetamol poisoning in children.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Femenino
/
Humanos
/
Masculino
/
Embarazo
/
Niño
/
Preescolar
/
Adolescente
/
Analgésicos no Narcóticos
/
Diagnóstico Diferencial
/
Relación Dosis-Respuesta a Droga
Tipo de estudio:
Estudio diagnóstico
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Pediatr
Año:
1998
Tipo del documento:
Artículo
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