A comparison of low vs standard dose intramuscularly administered hepatitis B vaccine.
Artículo
en Inglés
| IMSEAR
| ID: sea-86195
ABSTRACT
In a randomised, controlled, single-blind trial we compared different doses of a yeast-derived recombinant hepatitis B vaccine a low dose intramuscular (i.m.) regimen (using 2 micrograms at first followed by 1 microgram each at 1, 2 and 6 months) with the standard dose (10 micrograms each at 0, 1 and 6 months) for post vaccination anti-HBs seropositivity. At the end of 7 months, only 78% of volunteers on the low dose (n = 77) tested positive for anti-HBs whereas 100% of volunteers on the standard dose (n = 43) were seropositive. Therefore, low dose regimen is not satisfactory for primary HBV vaccination.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Femenino
/
Humanos
/
Masculino
/
Método Simple Ciego
/
Vacunas contra Hepatitis B
/
Adulto
/
Relación Dosis-Respuesta a Droga
/
Hepatitis B
/
Anticuerpos contra la Hepatitis B
/
Inyecciones Intramusculares
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Año:
1994
Tipo del documento:
Artículo
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