A clinico-haematologic profile of paroxysmal nocturnal haemoglobinuria.
Artículo
en Inglés
| IMSEAR
| ID: sea-87026
ABSTRACT
Clinico-haematological parameters in sixteen patients of paroxysmal nocturnal haemoglobinuria (PNH) are presented. Their modes of presentation included recurrent episodes of cola-coloured urine (6/16), refractory anaemia (9/16) and predominant thrombotic manifestations (1/16). Laboratory investigations revealed the presence of anaemia (16/16), reticulocytosis (14/16), thrombocytopenia (11/16), leucopenia (5/16) and cellular bone marrow (14/16). Two patients had hypoplastic bone marrow initially but subsequently developed PNH. The patients were treated with haematinics, prednisolone (16/16) and oxymethalone (2). Prednisone was effective in suppressing haemolytic episodes. Oxymethalone given to the 2 patients with hypoplastic bone marrow resulted in amelioration of anaemia in one but no effect in the other patient.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Oximetolona
/
Recurrencia
/
Trombocitopenia
/
Médula Ósea
/
Anemia Refractaria
/
Femenino
/
Humanos
/
Masculino
/
Prednisolona
/
Adolescente
Idioma:
Inglés
Año:
1991
Tipo del documento:
Artículo
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