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A prospective study of delta infection in fulminant hepatic failure.
Artículo en Inglés | IMSEAR | ID: sea-89504
ABSTRACT
Thirty one patients of HBV related Fulminant Hepatic Failure (FHF) were studied for the presence of delta infection and subsequently the clinical features, course and outcome of the delta infected cases was compared with those of delta uninfected cases. Out of 31 patients studied, 11 patients (35.8%) were reactive for anti-delta antibodies. There was no significant difference in age in delta reactive and non-reactive group. Hepatic encephalopathy was seen in all of the patients. The mean SGOT and SGPT were 378 +/- 88.74 U and 454 +/- 70.44 U respectively in anti-delta reactive group as compared to 239 +/- 74.94 U and 274.1 +/- 100.34 U respectively in anti-delta non reactive group (p < 0.05). During follow up, 10/11 patients (91%) died in anti-delta reactive group as compared to 13/20 patients (65%) in anti-delta non reactive group. So this study suggests that delta virus infection is quite common in India and it lead to excerbation of illness and carries a relatively poor prognosis for FHF.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Hepatitis D / Femenino / Humanos / Masculino / Estudios Prospectivos / Adulto Tipo de estudio: Estudio observacional / Factores de riesgo Idioma: Inglés Año: 1996 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Hepatitis D / Femenino / Humanos / Masculino / Estudios Prospectivos / Adulto Tipo de estudio: Estudio observacional / Factores de riesgo Idioma: Inglés Año: 1996 Tipo del documento: Artículo