Acute superior mesenteric vein thrombosis associated with factor V 'Leiden' gene mutation.
Artículo
en Inglés
| IMSEAR
| ID: sea-91364
ABSTRACT
OBJECTIVES:
To study thrombophilia states in Indian patients with acute spontaneous superior mesenteric vein thrombosis (SMVT).METHODS:
Two men with this condition, a 56 year old and a 31 year old presenting with acute SMVT, demonstrated on CT scan, were subjected to a thrombophilia screen consisting of Protein C, S, antithrombin levels, lupus anticoagulant, anticardiolipin antibodies, fibrinogen levels, factor VIII levels, factor V 'Leiden' gene mutation, and paroxysmal nocturnal hematuria screen.RESULTS:
A thrombophilia screen showed factor V 'Leiden' gene mutation (heterozygous) in both cases. Additionally, the first patient had high fibrinogen levels and the second high factor VIII levels. Both patients are currently on long-term anticoagulation.CONCLUSION:
Factor V 'Leiden' gene mutation in association with other thrombophilic factors may predispose to spontaneous superior mesenteric vein thrombosis.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Masculino
/
Factor V
/
Enfermedad Aguda
/
Adulto
/
Trombofilia
/
Trombosis de la Vena
/
Heterocigoto
/
Oclusión Vascular Mesentérica
/
Venas Mesentéricas
Idioma:
Inglés
Año:
2003
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS