Choice of antibiotics for empiric treatment of serious infections.

ABSTRACT

We have compared the in vitro activity of commonly used aminoglycosides--Gentamicin and Amikacin with Ciprofloxacin to determine whether the latter has any role in the empiric treatment of serious bacterial infections. Our results indicate that ciproloxacin was comparable or had a better activity than gentamicin or Amikacin against clinical isolates. As it can be administered orally, hospitalization can be avoided in a large number of patients.