Phenytoin induced severe disabling osteomalacia in a young male with seizure disorder.
Artículo
en Inglés
| IMSEAR
| ID: sea-94819
ABSTRACT
While the use of anti epileptic drugs (AEDs) for a long period is a known risk factor for bone loss and pathological fractures, yet the physicians are not yet sensitized to this possibility. It is now believed that the patients who have fractures due to long-term treatment with anticonvulsants have osteomalacia as the predominant lesion. This has been attributed to the alterations in the levels of circulating calcium and calcitropic hormones. Here we report a case of a young male who had been on anticonvulsants for 11 years and was admitted with us with severe bone pains, multiple pathological pseudo fractures and a severe degree of disability secondary to phenytoin induced osteomalacia.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Osteomalacia
/
Fenitoína
/
Humanos
/
Masculino
/
Adolescente
/
Epilepsia Tónico-Clónica
/
Cuidados a Largo Plazo
/
Evaluación de la Discapacidad
/
Encefalitis
/
India
Tipo de estudio:
Factores de riesgo
País/Región como asunto:
Asia
Idioma:
Inglés
Año:
2008
Tipo del documento:
Artículo
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