Prognosis and management of membraneous nephropathy.
Artículo
en Inglés
| IMSEAR
| ID: sea-95307
ABSTRACT
Patients of idiopathic membranous nephropathy (MGN) were randomly assigned to received steroid and cyclophosphamide every other month (Gr-I) and steroid alone (Gr-II). Of 36 patients in Gr.I, 33 patients achieved complete remissions, 2 had relapsing course with remission on further courses of therapy and only one has reached end stage renal failure. In contrast, of the 35 patients in Gr. II, 15 (P < 0.001) achieved complete remission, 7 are in partial remission, 5 have no response, another 5 have deterioration of renal function of which two required dialysis, and 3 have relapsing course after the initial remission. Mean follow up period was 46 +/- 10.2 months. We conclude that steroid and cyclophosphamide every other month is highly effective in achieving remission in patients with membranous nephropathy.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pronóstico
/
Anciano
/
Femenino
/
Humanos
/
Masculino
/
Esquema de Medicación
/
Prednisolona
/
Glomerulonefritis Membranosa
/
Estudios de Seguimiento
/
Adolescente
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Año:
1993
Tipo del documento:
Artículo
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