Alprazolam in chronic tension type headache.
Artículo
en Inglés
| IMSEAR
| ID: sea-95398
ABSTRACT
Alprazolam was evaluated in the treatment of 62 patients of chronic tension type headache using a double blind cross over design with random allocation to drug or placebo. The duration of the trial was 4 months with a 2 week run in period and 2 week washout period separating two treatment periods of 4 weeks each. The patients were followed up for 4 weeks at the completion of the trial. 48 patients completed the trial. There was no significant difference in the overall response rate based in terms of percentage reduction in headache frequency per week, however a significant decrease in headache index was observed during treatment with alprazolam as compared to placebo (P < 0.05). The mean analgesic intake per week was also significantly lower during treatment with alprazolam as compared to the run in period. Side effects were seen in 16.67% patients. In none of the patients was it significant enough to require withdrawal from the study.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Alprazolam
/
Femenino
/
Humanos
/
Masculino
/
Método Doble Ciego
/
Enfermedad Crónica
/
Estudios de Seguimiento
/
Resultado del Tratamiento
/
Cefalea de Tipo Tensional
/
Estudios Cruzados
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Año:
1996
Tipo del documento:
Artículo
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