Hypotension in preterm infants.
Indian Pediatr
;
2008 Apr; 45(4): 285-94
Artículo
en Inglés
| IMSEAR
| ID: sea-9826
ABSTRACT
PURPOSE:
Hypotension is a frequent occurrence in sick preterm neonates. It is important to appropriately recognise and treat hypotension in preterm infants due to the possible association with short and long term adverse outcomes. SEARCH STRATEGY An extensive search for relevant articles was carried out on PubMed, Embase and Cochrane database of systematic reviews. Cross references were hand searched.CONCLUSIONS:
The pathophysiology hypotension in preterm infants is multifactorial. Hypovolemia plays only a minor role in the absence of overt fluid losses. Cardiac dysfunction seems to be a factor in some neonates. Assessment of hypotension should be based on an overall clinical condition. Overzealous fluid administration seems to be associated with adverse outcomes and should be avoided in the absence of obvious fluid losses. Inotropes should be used if fluid boluses fail to correct hypotension. Dopamine is the most effective inotrope. Dobutamine can be used as add on therapy or as first line if cardiac dysfunction is an obvious cause. Evidence points to hypocortisolism in at least some hypotensive infants. Steroids have been used successfully in inotrope-resistant hypotension in some infants. Steroids should be used judiciously since there have been concerns about adverse neurological outcome in preterm infants who received steroids in the neonatal period.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Simpatomiméticos
/
Factores de Tiempo
/
Presión Sanguínea
/
Humanos
/
Recién Nacido
/
Recien Nacido Prematuro
/
Gasto Cardíaco
/
Cardiotónicos
/
Dopamina
/
Factores de Riesgo
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
2008
Tipo del documento:
Artículo
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