Growth pattern and final height in 21-hydroxylase deficiency.
Indian Pediatr
;
2007 Oct; 44(10): 771-3
Artículo
en Inglés
| IMSEAR
| ID: sea-9974
ABSTRACT
Growth pattern and final height were evaluated in 47 children with 21-hydroxylase deficiency to identify factors influencing growth. The subjects were followed-up from the age of 0.6 +/- 1.2 years for 8.8 +/- 3.9 years. Final height SDS was significantly below target height SDS (- 2.5 +/- 1.4 versus - 1.0 +/- 1.0, P < 0.001). Laboratory monitoring and type of disease (salt-wasting or simple virilizing) significantly influenced age-specific height SDS. Age at treatment, frequency of laboratory monitoring and dose of glucocorticoid during infancy influenced final height on univariate analysis; the effect was not sustained on multivariate analysis. Our study emphasizes the need for regular laboratory monitoring and lower glucocorticoid dose during infancy in 21-hydroxylase deficiency.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Estatura
/
Femenino
/
Humanos
/
Masculino
/
Niño
/
Desarrollo Infantil
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Adolescente
/
Hiperplasia Suprarrenal Congénita
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
2007
Tipo del documento:
Artículo
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