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Growth pattern and final height in 21-hydroxylase deficiency.
Indian Pediatr ; 2007 Oct; 44(10): 771-3
Artículo en Inglés | IMSEAR | ID: sea-9974
ABSTRACT
Growth pattern and final height were evaluated in 47 children with 21-hydroxylase deficiency to identify factors influencing growth. The subjects were followed-up from the age of 0.6 +/- 1.2 years for 8.8 +/- 3.9 years. Final height SDS was significantly below target height SDS (- 2.5 +/- 1.4 versus - 1.0 +/- 1.0, P < 0.001). Laboratory monitoring and type of disease (salt-wasting or simple virilizing) significantly influenced age-specific height SDS. Age at treatment, frequency of laboratory monitoring and dose of glucocorticoid during infancy influenced final height on univariate analysis; the effect was not sustained on multivariate analysis. Our study emphasizes the need for regular laboratory monitoring and lower glucocorticoid dose during infancy in 21-hydroxylase deficiency.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Estatura / Femenino / Humanos / Masculino / Niño / Desarrollo Infantil / Estudios Retrospectivos / Estudios de Seguimiento / Adolescente / Hiperplasia Suprarrenal Congénita Tipo de estudio: Estudio observacional / Estudio pronóstico Idioma: Inglés Revista: Indian Pediatr Año: 2007 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Estatura / Femenino / Humanos / Masculino / Niño / Desarrollo Infantil / Estudios Retrospectivos / Estudios de Seguimiento / Adolescente / Hiperplasia Suprarrenal Congénita Tipo de estudio: Estudio observacional / Estudio pronóstico Idioma: Inglés Revista: Indian Pediatr Año: 2007 Tipo del documento: Artículo