Effect of Basic Fibroblast Growth Factor on Fibrovascular Ingrowth into Porous Polyethylene Anophthalmic Socket Implants
Korean Journal of Ophthalmology
;
: 1-8, 2005.
Artículo
en Inglés
| WPRIM
| ID: wpr-100227
ABSTRACT
To investigate the effect of basic Fibroblast Growth Factor (bFGF) on fibrovascular ingrowth into porous polyethylene orbital implants (Medpor (R) ) and to investigate any differences according to the method of administration. For the treated groups, after evisceration and Medpor (R) implantation, bFGF was administered by soaking Medpor (R) in the bFGF solution, and/or by injecting bFGF into the Medpor (R) 1 week after the operation. Implants were removed 4 weeks after the operation and examined for the degrees of fibrovascular ingrowth by light microscopy. The percentages of the cross-sectional area of the implant occupied by fibrovascular ingrowth and the numbers of proliferated vessels were significantly higher in the bFGF-treated groups (Mann Whitney test, p 0.05). bFGF promoted fibrovascular ingrowth into porous polyethylene orbital implants regardless of the route of administration. Therefore, bFGF might be helpful to prevent complications such as implant exposure.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Factor 2 de Crecimiento de Fibroblastos
/
Porosidad
/
Evisceración del Ojo
/
Neovascularización Fisiológica
/
Implantación de Prótesis
/
Implantes Orbitales
/
Polietileno
/
Fibroblastos
Límite:
Animales
Idioma:
Inglés
Revista:
Korean Journal of Ophthalmology
Año:
2005
Tipo del documento:
Artículo
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