Expression of Angiopoietin-1 and Angiopoietin-2 mRNA in Eutopic and Ectopic Endometrium / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1171-1178, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-100308
ABSTRACT
OBJECTIVE:
To investigate the mRNA expression of Angiopoietin (Ang)-1 and Ang-2 in ectopic and eutopic endometrium from women with or without endometriosis throughout the menstrual cycle.METHODS:
Total RNA was extracted and reverse transcribed into cDNA. The expression of Ang-1 and Ang-2 was examined by quantative competitive PCR (QC PCR) and each result was analyzed by Kruskal- Wallis analysis and Mann-Whitney U-test.RESULTS:
The expression of Ang-1 mRNA was statistically significantly higher in endometrium of follicular phase from women with endometriosis compared to that from normal ones in the follicular phase. Endometriotic tissues expressed significantly lower Ang-2 mRNA compared to endometrium from women without endometriosis.CONCLUSION:
We suggested that the expression of Ang-1 mRNA could be associated with the pathogenesis of endometriosis and might have a role as neovascularizaton and survival of ectopic endometrium.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
ARN
/
ARN Mensajero
/
Reacción en Cadena de la Polimerasa
/
ADN Complementario
/
Angiopoyetina 1
/
Angiopoyetina 2
/
Endometriosis
/
Endometrio
/
Fase Folicular
/
Ciclo Menstrual
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Año:
2004
Tipo del documento:
Artículo
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