PHYTOCHEMICAL STUDY OF PLANTS THAT HAVE IMMUNE SYSTEM SUPPORTING FUNCTION / Монголын эм зүй, эм судлал

ABSTRACT

Background: In recent years the number of diseases that arise from compromised immune system has been steadily such as autoimmune and immunity expressing cleseases, research has been going on order to deverlop a highly effective medicine made from natural resources, with low risk of increasing toxicity and side effects that can be used to treat or prevent these diseases. Throughout the world, there are a number of plants that have been identified with immune boosting ability and the following plants Astragalus mongolicus Bunge , Salsola laricifolia Turcz, Oxytropis pseudoglandulosa Gontsch, Inula helenium that have been proven to support the immune system and grow in Mongolia were selected for a phytochemical study. Goal An objective was set forth to identify a proper extragent (extraction solvent) to extract the biologically active compounds found in Astragalus mongolicus Bunge , Salsola laricifolia Turcz, Oxytropis pseudoglandulosa Gontsch, Inula helenium plants known to stimulate immune function. Results: Salsola laricifolia’s coumarin content was the highest or 0.33% when extracted with 60% alcohol, the flavonoid content was 0.56% when 55%, 60% alcohol was used as the extragent, 60% alcohol is determined to be an appropriate extragent. Astragalus mongolicus’s coumarin and flavonoid composition was quite high in 25% alcohol, specifically it contained 0.04% coumarin and 0.20% flavonoid. Inula helenium’s 50% alcohol extract contained 0.25% coumarin, 25% alcohol extract had a flavonoid content of 0.59% and 50% alcohol is determined to be proper extragent in future research Oxytropis pseudoglandulosa’s 50% alcohol contained 0.65% coumarin and 0.7% flavonoid, therefore 50% alcohol will be used to extract this plant for furthrer research