Clinical effect of blood transfusion inpremature infants with anemia of different severity / 中国输血杂志

ABSTRACT

【Objective】 To explore the clinical effect of blood transfusion in children with anemia of different severity. 【Methods】 135 premature infants admitted to our hospital from January 2018 to December 2019 were selected as research subjects. They were divided into study group(n=99) and the control group(n=36) according to the presence or absence of anemia. The children in the study group were treated with red blood cell transfusion, and the vital signs, Hb, Hct and tissue oxygen saturation of the two groups were compared. 【Results】 After treatment, HR of severe anemicgroup was (118.4±9.2) times/min, which was significantly lower than that of control group as (127.1±12.4) times/min and mildanemic group as (125.7±11.5) times/min; RR of severe anemic group was (25.0±4.7) times/min, which was significantly lower than that of control group as (30.4±5.9) times/min and mild anemic group as(28.5±5.6) times/min.And the differences were statistically significant (P<0.05). After treatment, Hb in severe anemicgroup and moderate anemic group were (140.3±6.5) g/L and (147.4±7.2) g/L, respectively, and Hct in severe anemic group and moderate anemic group were (0.43±0.02) L/L and (0.46±0.02) L/L respectively, which were significantly higher than those before treatment (P<0.05). After treatment, cerebral oxygen saturation and intestinal tissue oxygen saturation of severe anemic group were (79.2±4.0)%and (80.0±4.3)%, which were significantly lower than those of control group (P<0.05). 【Conclusion】 Blood transfusion treatment can significantly improve Hb and Hct levels, as well astissue oxygen saturationof premature infants.