Storage duration of suspendedred blood cells affects the efficacy of blood transfusion in patients with aplastic anemia / 中国输血杂志

ABSTRACT

【Objective】 To study the impact of the storage duration of suspendedred blood cells(RBCs)on blood transfusion for patients with aplastic anemia. 【Methods】 76 occasions of blood transfusions for 36 patients with aplastic anemia, admitted to our hospital between 2017~2019, were observed. The effects of patient and donordemographics as well as storage duration on the efficacy of RBCs transfusion were analyzed using linear regression. 【Results】 Multivariate linear regression analysis revealed that the efficacy of RBCs transfusion was negatively correlated with the patient′s weight (P0.05) and -1.904 (95% CI -3.750~-0.057; P<0.05) g/L, respectively, presenting a gradually decreasing trend. 【Conclusion】 Longer storage of RBCs has an impact on the efficacy of blood transfusion in patients with aplastic anemia.