Effectiveness of 100% tea tree oil (Melaleuca alternifolia) versus salicylic acid + lactic acid solution in the treatment of common warts: A randomized controlled trial

ABSTRACT

Background@#Common warts are a common malady among patients. Not only does it affect the person physically but also mentally and socially. Several treatment modalities are available; however, the major concerns are the treatment cost and adverse effect profile. Salicylic + lactic acid (SLA) solution is one of the standard treatment modalities owing to its strong keratolytic properties; however, its cost and adverse effects limit its use among patients. A cost-effective and safe alternative treatment is ideal to bring about a more favorable clinical outcome and better patient satisfaction. 100% tea tree oil (TTO) solution was used in this study due to its natural antiviral and anti-inflammatory properties.@*Objective@#The study aimed to compare the safety and effectiveness of 100% TTO versus SLA solution in the treatment of common warts.@*Methods@#A total of 17 patients with a total of 74 warts were included in the study. Each wart was assigned to either of the two treatment groups. the SLA group and the 100% TTO group. A treatment period of 6 weeks was used to assess the effectiveness of both treatment groups.@*Results@#The study showed no significant difference between the SLA solution and 100% TTO in the treatment of common warts. The 100% tea tree group reported lesser adverse effects. Both treatment groups reported favorable treatment satisfaction.@*Conclusion@#100% TTO is a potentially safe and cost-effective alternative in the treatment of common warts.