Exploration of modern scientific connotation of Miao medicine Qizu Xueyu syndrome and intervention mechanism of Kangfuyan Capsules / 中国中药杂志

ABSTRACT

The aim of this paper was to explore the modern scientific connotation of Qizu Xueyu syndrome in Miao medicine and the intervention mechanism of Kangfuyan Capsules on Qizu Xueyu syndrome. Under the guidance of the theory of Miao medicine,an experimental animal model was constructed to characterize Qizu Xueyu syndrome in Miao medicine,and its modern scientific connotation was explored from the perspectives of general signs,blood lipid index,serum biochemical index and immune index. Furthermore,the relevant experimental animals were given Kangfuyan Capsules for intervention,then observed the corrective effect of Kangfuyan Capsules on abnormal physiological and biochemical indexes of the experimental animal model. The model animals showed signs such as mental depression,rough coat,dull and glossy,and the writhing behavior changed significantly. Low density lipoprotein cholesterol,creatine phosphate kinase,Ig G,urea nitrogen,creatinine,direct bilirubin,urea,urinary biliary and liver index were significantly higher than those in the blank group( P< 0. 01). The blood sugar and thymus index were significantly lower than those in the blank group( P <0. 01). After the intervention of Kangfuyan Capsules,the physiological and mental state of the experimental animals improved,their weight increased and their writhing behavior improved. Creatine phosphate kinase( CK) was significantly higher than that of Qizu Xueyu group( P<0. 01),direct bilirubin was significantly lower than that of Qizu Xueyu group( P<0. 01),immune indexes had no significant difference,urinary bilirubin returned to normal. The modern scientific connotation of Qizu Xueyu syndrome in Miao medicine can be characterized by ischemia,tissue and cell damage,infection and abnormal liver and kidney function caused by smooth muscle spasm. Kangfuyan Capsules can relieve uterine smooth muscle spasm,improve local blood circulation,repair muscle cell injury,protect liver and improve renal function.