A new cytotoxic flavone from Cassia nomame / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4203-4206, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-1008280
ABSTRACT
A new flavone( 1) has been isolated from the whole plant of Cassia nomame by using various chromatographic techniques,including silica gel,Sephadex,MCI-gel resin,and RP-HPLC,and its structure was determined as 8,4'-dimethoxy-7-( 2-oxopropyl)-flavone based on spectroscopic data. The biological activity test showed that this compound displayed potent cytotoxicity against NB4,SH-SY5 Y,PC3,A549 and MCF-7 cell lines with IC50 values 2. 2,1. 8,3. 4,4. 5 and 1. 6 μmol·L-1,respectively.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Cassia
/
Cromatografía Líquida de Alta Presión
/
Senna
/
Flavonas
/
Células MCF-7
Límite:
Humanos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2019
Tipo del documento:
Artículo
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