Biomechanical properties of epithelial mesenchymal transition in idiopathic pulmonary fibrosis / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 632-637, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-1008882
ABSTRACT
Idiopathic pulmonary fibrosis (IPF) is a progressive scar-forming disease with a high mortality rate that has received widespread attention. Epithelial mesenchymal transition (EMT) is an important part of the pulmonary fibrosis process, and changes in the biomechanical properties of lung tissue have an important impact on it. In this paper, we summarize the changes in the biomechanical microenvironment of lung tissue in IPF-EMT in recent years, and provide a systematic review on the effects of alterations in the mechanical microenvironment in pulmonary fibrosis on the process of EMT, the effects of mechanical factors on the behavior of alveolar epithelial cells in EMT and the biomechanical signaling in EMT, in order to provide new references for the research on the prevention and treatment of IPF.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Transducción de Señal
/
Fibrosis Pulmonar Idiopática
/
Transición Epitelial-Mesenquimal
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2023
Tipo del documento:
Artículo
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