Research progress on the role of monocytes in viral hemorrhagic fevers / 细胞与分子免疫学杂志
Chinese Journal of Cellular and Molecular Immunology
; (12): 748-752, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1009426
Biblioteca responsable:
WPRO
ABSTRACT
Monocytes are important target cells of various hemorrhagic fever viruses. In viral hemorrhagic fevers (VHFs), monocytes can be infected by viruses and produce different kinds of cytokines, which contribute to the antiviral immune response and participation in the immunopathogenesis of VHFs. During the pathogenesis of various VHFs (early stage), monocytes change in cell counting, subpopulation distribution and expression of surface molecules with an activated phenotype. Several hemorrhagic fever viruses can infect monocytes and induce immune response, which may play an important role in immunopathological injury. Monocytes and the cytokines they produce may interact with platelets and vascular endothelial cells, contributing to disease progression.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Monocitos
/
Citocinas
/
Células Endoteliales
/
Fiebres Hemorrágicas Virales
/
Inmunidad
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Cellular and Molecular Immunology
Año:
2023
Tipo del documento:
Article