Research progress in vaccines of SARS-CoV-2 / 细胞与分子免疫学杂志
Chinese Journal of Cellular and Molecular Immunology
;
(12): 946-951, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-1009452
ABSTRACT
Since the outbreak of corona virus disease 2019 (COVID-19), viral strains have mutated and evolved. Vaccine research is the most direct and effective way to control COVID-19. According to different production mechanisms, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines included inactivated virus vaccine, live attenuated vaccine, mRNA vaccine, DNA vaccine, viral vector vaccine, virus-like particle vaccine and protein subunit vaccine. Among them, viral protein subunit vaccine has a wide application prospect due to its high safety and effectiveness. Viral nucleocapsid protein has high immunogenicity and low variability which could be a new direction for vaccine production. We summarized the current development of vaccine research by reviewing the current progress, vaccine safety and vaccine immune efficiency. It is hoped that the proposed possible development strategies could provide a reference for epidemic prevention work in future.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vacunas de ADN
/
Proteínas de la Nucleocápside
/
Subunidades de Proteína
/
SARS-CoV-2
/
COVID-19
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Cellular and Molecular Immunology
Año:
2023
Tipo del documento:
Artículo
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