Your browser doesn't support javascript.
loading
Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B ; (12): 57-64, 2018.
Artículo en Inglés | WPRIM | ID: wpr-1010368
ABSTRACT
OBJECTIVE@#The purpose of this meta-analysis was to explore the effect of corticosteroids on atrial fibrillation (AF) following catheter ablation.@*METHODS@#We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for published articles describing the effect of corticosteroids in preventing AF recurrence after catheter ablation. Data on study and patient were extracted. Risk ratios (RRs) and 95% confidence intervals (CIs) were calculated by use of a random-effect model, and P values of <0.05 were considered significant.@*RESULTS@#Two randomized controlled trials (RCTs) and three cohort studies involving 846 patients were included in this meta-analysis. Within one month of catheter ablation, corticosteroid use was associated with a declined risk of recurrence of AF in RCT (RR 0.57, 95% CI 0.39 to 0.85, P=0.005), but without significant effect in cohort studies (RR 1.01, 95% CI 0.79 to 1.30, P=0.94). After three months of catheter ablation, corticosteroids did not have a significant effect in the prevention of late recurrence of AF in either RCT (RR 0.78, 95% CI 0.38 to 1.59, P=0.49) or cohort studies (RR 0.96, 95% CI 0.70 to 1.31, P=0.78).@*CONCLUSIONS@#Our meta-analysis suggested that periprocedural administration of corticosteroids of catheter ablation was associated with reduction of early but not late recurrence of AF.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Fibrilación Atrial / Oportunidad Relativa / Ensayos Clínicos Controlados Aleatorios como Asunto / Factores de Riesgo / Estudios de Cohortes / Resultado del Tratamiento / Ablación por Catéter / Corticoesteroides Límite: Anciano / Humanos Idioma: Inglés Revista: Journal of Zhejiang University. Science. B Año: 2018 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Fibrilación Atrial / Oportunidad Relativa / Ensayos Clínicos Controlados Aleatorios como Asunto / Factores de Riesgo / Estudios de Cohortes / Resultado del Tratamiento / Ablación por Catéter / Corticoesteroides Límite: Anciano / Humanos Idioma: Inglés Revista: Journal of Zhejiang University. Science. B Año: 2018 Tipo del documento: Artículo