Molecular mechanisms of cellular metabolic homeostasis in stem cells / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 52-52, 2023.
Artículo
en Inglés
| WPRIM
| ID: wpr-1010707
ABSTRACT
Many tissues and organ systems have intrinsic regeneration capabilities that are largely driven and maintained by tissue-resident stem cell populations. In recent years, growing evidence has demonstrated that cellular metabolic homeostasis plays a central role in mediating stem cell fate, tissue regeneration, and homeostasis. Thus, a thorough understanding of the mechanisms that regulate metabolic homeostasis in stem cells may contribute to our knowledge on how tissue homeostasis is maintained and provide novel insights for disease management. In this review, we summarize the known relationship between the regulation of metabolic homeostasis and molecular pathways in stem cells. We also discuss potential targets of metabolic homeostasis in disease therapy and describe the current limitations and future directions in the development of these novel therapeutic targets.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Madre
/
Diferenciación Celular
/
Homeostasis
Idioma:
Inglés
Revista:
International Journal of Oral Science
Año:
2023
Tipo del documento:
Artículo
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