A review of structural modification and biological activities of oleanolic acid / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 15-30, 2024.
Artículo
en Inglés
| WPRIM
| ID: wpr-1011008
ABSTRACT
Oleanolic acid (OA), a pentacyclic triterpenoid, exhibits a broad spectrum of biological activities, including antitumor, antiviral, antibacterial, anti-inflammatory, hepatoprotective, hypoglycemic, and hypolipidemic effects. Since its initial isolation and identification, numerous studies have reported on the structural modifications and pharmacological activities of OA and its derivatives. Despite this, there has been a dearth of comprehensive reviews in the past two decades, leading to challenges in subsequent research on OA. Based on the main biological activities of OA, this paper comprehensively summarized the modification strategies and structure-activity relationships (SARs) of OA and its derivatives to provide valuable reference for future investigations into OA.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ácido Oleanólico
/
Relación Estructura-Actividad
/
Triterpenos
/
Antiinflamatorios
/
Antibacterianos
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2024
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS