Fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation / 中华血液学杂志
Chinese Journal of Hematology
; (12): 853-855, 2019.
Article
en Zh
| WPRIM
| ID: wpr-1012080
Biblioteca responsable:
WPRO
ABSTRACT
Objective: To explore the availability and safety of fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation (allo-HSCT) . Methods: Four acute leukemia patients suffered from refractory diarrhea after allo-HSCT. One of them was refractory intestinal infection, the others were intestinal graft versus host disease. One or two doses of fecal microbiota, 3.4-6.0 U for one dose, were infused via nasal-jejunal tube. The curative effect and side effects were reviewed. Results: Three cases achieved complete remission while 1 was stable disease. The side effects included fever, abdominal pain and diarrhea, which all were Ⅰ grade. Conclusion: Fecal microbiota transplantation was effective and safe for refractory diarrhea after allo-HSCT.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Leucemia Mieloide Aguda
/
Trasplante de Células Madre Hematopoyéticas
/
Diarrea
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Trasplante de Microbiota Fecal
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Enfermedad Injerto contra Huésped
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Hematology
Año:
2019
Tipo del documento:
Article