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Regulatory effect and mechanism of macrophage polarization in liver fibrosis / 临床肝胆病杂志
Journal of Clinical Hepatology ; (12): 611-615, 2024.
Artículo en Chino | WPRIM | ID: wpr-1013146
ABSTRACT
Liver fibrosis is the healing reaction of chronic liver injury caused by various factors such as viral infection, alcohol, and chemical substances and is a key link in the progression of chronic liver diseases to liver cirrhosis and liver cancer. Liver macrophages are considered important mediators of liver injury and repair, and the polarization trend of macrophages has a bidirectional regulatory effect on liver fibrosis. This article reviews the role of different phenotypes of liver macrophages in the development and progression of liver fibrosis, in order to provide new ideas for the prevention and treatment of fibrosis.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Clinical Hepatology Año: 2024 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Journal of Clinical Hepatology Año: 2024 Tipo del documento: Artículo