Homoharringtonine activates ATM/p53 pathway to inhibit proliferation of human liver cancer cell PLCS / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 380-385, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-1014346
ABSTRACT
Aim To explore the effect of homoharringtonine (HHT) on the prohferation of liver cancer cell PLCS and its possible mechanism. Methods CCK-8 and EdU were used to detect the effect of HHT on the proliferation of PLCS cells; flow cytometry was employed to assess the effect of HHT on cell cycle of PLCS; Western blot was applied to measure the expression levels of cycle-related proteins cyclinA, CDK 2, p 2 1, p53 and A T M. Results Treated with HHT (0, 5, 10, 20, 40, 80 • L
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Pharmacological Bulletin
Año:
2021
Tipo del documento:
Artículo
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